Two women playing tennis together
A senior man in his allotment showing off his home grown vegetables with his son

The NHS-Galleri trial is investigating a new blood test to see if it can help the NHS detect cancer earlier, when it is easier to treat. The research team would like 140,000 people aged 50 to 77 to give blood samples and take part in the NHS-Galleri trial.

Through this trial, the research team can better understand if using the Galleri™ test alongside standard cancer testing in the NHS can help to find cancers at an early stage.

Who can take part

You can volunteer to take part in the trial if you get an invitation letter from the NHS and all of the following are true:

People

You are aged 50 to 77

Heart

You have not been diagnosed or treated for cancer in the last 3 years

Home

You live in one of the areas where the trial is being run

The trial is taking part in the following regions in England known as Cancer Alliances:

  • Cheshire and Merseyside
  • East of England (North)
  • Greater Manchester
  • Kent and Medway
  • East Midlands
  • West Midlands
  • Northern
  • South East London

Cancer Alliances bring together clinical and managerial leaders from different hospital trusts and other health and social care organisations, to transform the diagnosis, treatment and care for cancer patients in their local area.

Who cannot take part

You cannot take part if you have been diagnosed or treated for cancer in the last 3 years or are currently having tests (or waiting for tests) due to suspected cancer.

Taking part is completely voluntary. It is entirely your choice. If you choose not to take part, or if you choose to leave the trial at any point, there are no consequences, and you do not need to give a reason why.

Your appointment

Where the trial is happening

If you choose to take part, you will be able to book an appointment at a mobile clinic in your local area.

Clinics will take place in large mobile units and smaller mobile vans. The clinics will mostly be located in supermarket car parks, where free parking is available. This should also make them accessible by public transport.

Changing your mind

If you volunteer to take part, you can also change your mind at any point during the trial. You can let the trial team know you do not want to take part anymore. You do not have to give a reason.

We’ll keep and use the information and samples from you that we have already collected but we won’t ask you to come for any further tests or provide any more information.

About your data

Benefits and risks of taking part

By taking part you’ll be contributing to research which may benefit people in the future. If the trial finds that the test can detect cancer earlier when used with standard cancer testing in the NHS, then more cancers could be successfully treated. This is because the earlier cancer is found, the better the chance of successful treatment.

The Galleri test is a new blood test that can detect signs of many different types of cancer in a sample of a person’s blood.

You may enjoy taking part as a way to learn more about health research. We cannot say if you will benefit directly from taking part.

The research team will try to make sure people who take part in the NHS-Galleri trial have a good trial experience. However, there are some risks you need to be aware of.

If you take part in the trial you will need to give a number of blood samples. Giving blood is generally safe but there are some possible side effects including:

  • discomfort
  • lightheadedness
  • infection

If the test detects a cancer signal, you could experience anxiety or distress. Like all screening tests, the Galleri test is not perfect and can give a wrong result. If the test detects a cancer signal and no cancer is found by the doctor, you may have had follow-up tests that were unnecessary. Those follow-up tests can have their own risks, such as radiation from scans, that you should discuss with your doctor before receiving them.

The research team will try to make sure people who take part in the NHS-Galleri trial have a good trial experience.